VIVIANE LOVATTO

Abstract:

Introduction: Individuals with dialytic chronic kidney disease often have autonomic nervous system (ANS) imbalances as well as disturbances in the hydroelectrolytic balance, which can negatively impact the cardiovascular system. Objective: To analyze the influence of serum sodium (sNa) on heart rate variability (HRV) in chronic dialytic renal patients. Methods: A cross-sectional study with a comparative approach was conducted with individuals of both sexes undergoing maintenance hemodialysis and a control group. Analysis of the dialysis volunteers' medical records, anthropometric assessment, HRV analysis at rest, in the time domain and frequency, and evaluation of the biochemical markers of renal function were performed. The volunteers were allocated into three groups, the normotremia dialysis group, with sNa values within the normal range; dialytic hyponatremia group, with sNa values lower than normal; and a control group without kidney disease. Results: the sample consisted of 32 volunteers, with control group = 10, normotremia dialysis group = 14 and dialytic hyponatremia group = 8 participants. No differences were found between groups in anthropometric and clinical variables. For the biochemical variables of renal function, there was a difference between control group vs normotremia dialysis group and dialytic hyponatremia group. HRV analysis in time domain showed that dialytic hyponatremia group presented a reduction in HRV compared to the other groups. While in domain frequency, normotremia dialysis group showed modulation with sympathetic predominance, while dialytic hyponatremia group showed modulation with parasympathetic predominance. Conclusion: the results suggest that in dialysis patients there is a reduction in HRV and that the state of hyponatremia intensifies cardiac dysautomy, which increases the risk of a cardiovascular event.

	COMPLETE TEXT
	UFG DIGITAL LIBRARY